Anti-ASC (TMS1) (Human) mAb,货号-规格：D086-3-100 μg/100 μL
免疫源(抗体)
Triton X-100 insoluble fraction of retinoic acid-treated HL-60 cells
反应性
[Gene ID]
Human[29108], Mouse(-), Rat(-)
MHC Allele
1 mg/mL in PBS/50% glycerol, pH 7.2
Anti-ASC (TMS1) (Human) mAb-Alexa Fluor® 647
| Mayor A et al. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol. 8, 497-503. (2007) |
| Masumoto J et al. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J Biol Chem. 274, 33835-8 (1999) |
| Masumoto J et al. Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues. J Histochem Cytochem. 49, 1269-75 (2001) |
| Masumoto J et al. Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos. Exp Cell Res. 262, 128-33 (2001) |
| Masumoto J et al. Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC. Biochem Biophys Res Commun. 280, 652-5 (2001) |
| Bryan NB et al. Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. J Inflamm (Lond). 7, 23 (2010) |
| Terasawa K et al. Epigenetic inactivation of TMS1/ASC in ovarian cancer. Clin Cancer Res. 10, 2000-6 (2004) |
