| Product name | APC anti-human CD8 | | Catalog no | FHA008 | | Size | 100 tests | | Concentration |
| | Storage Buffer | Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA | | Storage Condition | Store at 4°C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL. | | Quality(Vol.) per. Test | 10 μl/test |
| Conjugate | APC | | Tested application | FC | | Clonality | Monoclonal | | Isotype | Mouse IgG1 | | Clone | 4ARiv11 | | Host | Mouse | | Reactivity | Human | | Description | 4ARiv11 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.* Ratio of CD4 and CD8 is important for monitor of HIV infection. |
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